TABLE 1.
Estimated costs of interventions per year per one million population applied in the study
| Interventions | Coverage (%) | Cost per year ($int, millions) per one million population [i.e., cost per capita] using 2000 base year | |
|---|---|---|---|
| Scenarios without gene drives | Insecticide‐treated bed nets (ITNs) | 50 | 0.47 |
| Insecticide‐treated bed nets (ITNs) | 80 | 0.63 | |
| Insecticide‐treated bed nets (ITNs) | 95 | 0.71 | |
| Case management with artemisinin‐based combination therapy (ACT) | 50 | 0.19 | |
| Case management with artemisinin‐based combination therapy (ACT) | 80 | 0.20 | |
| Case management with artemisinin‐based combination therapy (ACT) | 95 | 0.21 | |
| Combination (ITNs and ACT) | 50 | 0.68 | |
| Combination (ITNs and ACT) | 80 | 0.82 | |
| Combination (ITNs and ACT) | 95 | 0.74 |
| Interventions | Coverage (%) | Cost per year ($int, millions) per one million population [i.e., cost per capita] using 2000 base year | ||
|---|---|---|---|---|
| Lower bound | Upper bound | |||
| Scenarios with gene drives | 300 gene drive mosquitoes with X‐shredder efficiencies = 1.0 alone | NA | 0.72 | 7.17 |
| ITNs plus gene drives with X‐shredder efficiencies = 0.95 and 1.0 | 80 | 1.35 | 7.80 | |
| ITNs plus gene drives with X‐shredder efficiencies = 0.95 and 1.0 | 95 | 1.43 | 7.88 | |
| ACT plus gene drives with X‐shredder efficiencies = 0.95 and 1.0 | 95 | 0.93 | 7.38 | |
| ITNs+ACT plus gene drives with X‐shredder efficiencies = 0.95 and 1.0 | 50 | 1.40 | 7.85 | |
| ITNs+ACT plus gene drives with X‐shredder efficiencies = 0.95 and 1.0 | 80 | 1.54 | 7.99 | |
| ITNs+ACT plus gene drives with X‐shredder efficiencies = 0.9, 0.95 and 1.0 | 95 | 1.46 | 7.91 | |