Table 1.
Clinical and Pathological Characteristics of the Entire Cohort
| All patients (n = 3756), n (%) | Lobectomy (n = 943), n (%) | Total thyroidectomy (n = 2813), n (%) | p | |
|---|---|---|---|---|
| Age, years | ||||
| <55 | 2455 (65) | 683 (72) | 1772 (63) | <0.0001 |
| ≥55 | 1301 (35) | 260 (28) | 1041 (37) | |
| Sex | ||||
| Female | 2894 (77) | 685 (73) | 2209 (79) | 0.0002 |
| Male | 862 (23) | 258 (27) | 604 (21) | |
| Pathology | ||||
| Papillary | 3606 (96) | 879 (93) | 2727 (97) | <0.0001 |
| Follicular | 81 (2) | 41 (4) | 40 (1) | |
| Hurthle cell | 69 (2) | 23 (2) | 46 (2) | |
| Papillary subgroups | ||||
| Tall cell | 277 (7) | 43 (5) | 234 (8) | <0.0001 |
| Occult sclerosing variant | 113 (3) | 31 (3) | 82 (3) | |
| Classical | 1089 (29) | 200 (21) | 889 (32) | |
| Columnar | 7 (0) | 0 (0) | 7 (0) | |
| Solid/trabecular | 17 (0) | 2 (0) | 15 (1) | |
| Follicular | 1074 (29) | 343 (36) | 731 (26) | |
| Others | 19 (1) | 5 (1) | 14 (0) | |
| Unknown | 1010 (27) | 255 (27) | 755 (27) | |
| ATA risk stratification | ||||
| Intermediate risk | 1091 (29) | 215 (23) | 876 (31) | <0.0001 |
| Low risk | 2665 (71) | 728 (77) | 1937 (69) | |
| pT stagea | ||||
| T1a | 1723 (46) | 413 (44) | 1310 (47) | 0.0135 |
| T1b | 1277 (34) | 309 (33) | 968 (34) | |
| T2 | 756 (20) | 221 (23) | 535 (19) | |
| Multifocality | ||||
| Yes | 1677 (45) | 244 (26) | 1433 (51) | <0.0001 |
| No | 1948 (52) | 614 (65) | 1334 (47) | |
| Unknown | 131 (3) | 85 (9) | 46 (2) | |
| Vascular invasion | ||||
| Yes | 292 (8) | 59 (6) | 233 (8) | <0.0001 |
| No | 3239 (86) | 757 (80) | 2482 (88) | |
| Unknown | 225 (6) | 127 (14) | 98 (4) | |
| Microscopic ETE | ||||
| Yes | 531 (14) | 84 (9) | 447 (16) | <0.0001 |
| No | 3224 (86) | 858 (91) | 2366 (84) | |
| Unknown | 1 (0) | 1 (0) | 0 (0) | |
| Positive margins | ||||
| Yes | 136 (4) | 19 (2) | 117 (4) | <0.0001 |
| No | 3420 (91) | 793 (84) | 2627 (93) | |
| Unknown | 200 (5) | 131 (14) | 69 (3) | |
a
According to the American Joint Committee Cancer, Eighth edition.
ATA, American Thyroid Association; ETE, extrathyroidal extension; pT, pathological tumor.