TABLE 1.
Frequencies of eight antibodies to H. pylori in sera from 16 Mongolian gerbils of ulcer group and hyperplastic group
| Immunoreactive band (kDa) | Reacting sera (%) froma
|
|
|---|---|---|
| Ulcer group (n = 4)b | Hyperplastic group (n = 12)c | |
| 160 | 100 | 92 |
| 150 | 75 | 75 |
| 120 | 75 | 75 |
| 110 | 75 | 83 |
| 30 | 100 | 92 |
| 26 | 100 | 33 |
| 25 | 75 | 17 |
| 20 | 100 | 50 |
Sera from gerbils of the ulcer group were diluted 1:4,000. Sera from gerbils of the hyperplastic group were diluted 1:1,250. Serum dilution of samples from the ulcer group was 3.2-fold greater than that of the hyperplastic group because the mean antibody-H. pylori IgG value of the ulcer group as measured by ELISA was about threefold greater than that of the hyperplastic group (605.1 AI versus 177.4 AI, respectively). The sera were taken at 26, 38, and 52 weeks after H. pylori inoculation.
One of five sera from the gerbils in the ulcer group was run short for Western blot analysis.
Seven of 19 sera of gerbils from the hyperplastic group were run short for Western blot analysis.