TABLE 3.
Accuracy of diagnostic tests for R. equi pneumonia
| Reference standard test | Diagnostic testa | Sensitivity (%) | Specificity (%) | Disease prevalenceb |
|---|---|---|---|---|
| TW fluid culture | PCR (VP) | 90.0 | 81.4 | 10/53 (18.9) |
| PCR (VP, 16S) | 70.0 | 88.4 | 10/53 (18.9) | |
| AGID | 75.0 | 80.0 | ||
| Final clinical diagnosis | TW fluid PCR (VP) | 100.0 | 90.6 | 14/46 (30.4) |
| TW fluid PCR (16S) | 78.6 | 68.8 | 14/46 (30.4) | |
| TW fluid PCR (VP, 16S) | 78.6 | 96.9 | 14/46 (30.4) | |
| TW fluid culture | 57.1 | 93.8 | 14/46 (30.4) | |
| AGID | 62.5 | 75.9 | 8/37 (21.6) | |
| Nasal swab PCR (VP) | 50.0 | 88.9 | 6/33 (18.2) | |
| Serum PCR (VP) | 12.5 | 88.9 | 8/35 (22.9) | |
| Buffy coat PCR (VP) | 11.1 | 86.7 | 9/39 (23.1) |
a
VP, PCR positive using VP primers; 16S, PCR positive using 16S primers.
b
Number of foals positive with the reference standard test divided by the total number of foals with results available for both the reference standard test and the diagnostic test being evaluated. (Values in parentheses are percentages.)