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. 2022 Jan 26;79(3):1–9. doi: 10.1001/jamapsychiatry.2021.3990

Table 2. Risk of Hospitalization Due to Psychosis in Individuals Ineligible (After Application of ≥1 Exclusion Criteria) vs Eligible (Persons Without Any Exclusion Criterion).

Eligibility Finnish cohort Swedish cohort
No. of individuals No. (%) with event Time to event/censoring, mean (SD), d HR (95% CI)a P value No. of individuals No. (%) with event Time to event/censoring, mean (SD), d HR (95% CI)a P value
Main outcome analyses: hospitalization due to psychosis, 12 mo
Eligible 3580 615 (17.2) 278 (130) 1.14 (1.04-1.24) .005 1619 240 (14.8) 273 (127) 1.47 (1.28-1.92) <.001
Ineligible 14 221 2609 (18.4) 257 (137) 5839 1174 (20.1) 248 (137)
Alternative time period 1: hospitalization due to psychosis, 6 mo
Eligible 3580 443 (12.4) 154 (56) 1.15 (1.03-1.27) .01 1619 166 (10.3) 156 (53) 1.49 (1.26-1.75) <.001
Ineligible 14 221 1939 (13.6) 147 (60) 5839 835 (14.3) 145 (60)
Alternative time period 2: hospitalization due to psychosis, 9 mo
Eligible 3580 537 (15.0) 218 (93) 1.15 (1.05-1.26) .004 1619 212 (13.1) 218 (89) 1.45 (1.25-1.69) <.001
Ineligible 14 221 2327 (16.4) 205 (98) 5839 1033 (17.7) 200 (99)

Abbreviation: HR, hazard ratio.

a

An HR >1 means higher risk in the ineligible group. Primary analyses were with 12-month follow-up and sensitivity analyses with 6 and 9 months.