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Comparison of methods for single EV analysis.
| Method | Protein, RNA, both | Multiplexing | Throughput | Cost |
|---|---|---|---|---|
| Digital PCR | Both | Yes | Moderate | $ $ $ |
| Digital ELISA | Protein | No | Moderate | $ $ |
| Flow cytometry | Both | Yes | High | $ $ $ |
| NTA | Both | No | High | $ $ |
| Raman | None | No | Low | $ $ $ |
| Microscopy | Both | Yes | Low | $ $ |
