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. 2022 Jan 13;8:815881. doi: 10.3389/fmed.2021.815881

Table 3.

Multivariate Cox regression of discontinuation after 1 year of Secukinumab treatment in the entire population.

β SE Wald p-value HR (95%CI)
Diagnosis (Ref. AxSpA) 2.511 1.042 5.812 0.016 12.32 (1.60–94.9)
Obesity (Ref. No) 0.933 0.479 3.795 0.051 2.54 (0.99–6.50)
Gender (Ref. Male) −1.229 1.047 1.377 0.241 0.29 (0.04–2.28)
Interactions
  Obesity*gender   (Ref. No woman obese) −3.075 1.147 7.193 0.007 0.046 (0.005–0.44)
  Diagnosis*gender   (Ref. No man PsA) −3.508 1.186 8.752 0.003 0.03 (0.003–0.31)

AxSpA, Spondyloarthritis; PsA, Psoriatic arthritis; SE, standard error.