Table 3.
Multivariate Cox regression of discontinuation after 1 year of Secukinumab treatment in the entire population.
| β | SE | Wald | p-value | HR (95%CI) | |
|---|---|---|---|---|---|
| Diagnosis (Ref. AxSpA) | 2.511 | 1.042 | 5.812 | 0.016 | 12.32 (1.60–94.9) |
| Obesity (Ref. No) | 0.933 | 0.479 | 3.795 | 0.051 | 2.54 (0.99–6.50) |
| Gender (Ref. Male) | −1.229 | 1.047 | 1.377 | 0.241 | 0.29 (0.04–2.28) |
| Interactions | |||||
| Obesity*gender (Ref. No woman obese) | −3.075 | 1.147 | 7.193 | 0.007 | 0.046 (0.005–0.44) |
| Diagnosis*gender (Ref. No man PsA) | −3.508 | 1.186 | 8.752 | 0.003 | 0.03 (0.003–0.31) |
AxSpA, Spondyloarthritis; PsA, Psoriatic arthritis; SE, standard error.