Table 4. Cox Proportional Hazards Models for 30-Day Mortality, by Shock Etiology.
Variables | HR (95% CI)a | ||||
---|---|---|---|---|---|
All | Cardiogenic shock | Septic shock | Hypovolemic shock | Other | |
Age | 1.04 (1.03-1.04)b | 1.02 (1.02-1.03)b | 1.03 (1.03-1.04)b | 1.04 (1.03-1.05)b | 1.05 (1.04-1.05)b |
Female sex | 1.00 (0.93-1.07) | 1.26 (1.12-1.42)b | 0.93 (0.83-1.04) | 0.84 (0.68-1.05) | 0.87 (0.73-1.04) |
Prior coronary disease | 0.86 (0.79-0.94)b | 0.93 (0.81-1.06) | 0.89 (0.76-1.03) | 0.63 (0.46-0.86)b | 1.04 (0.82-1.31) |
Hypertension | 0.78 (0.72-0.84)b | 0.79 (0.70-0.89)b | 0.76 (0.67-0.86)b | 0.90 (0.71-1.14) | 0.80 (0.66-0.97)c |
Chronic kidney disease | 1.25 (1.10-1.42)b | 1.20 (0.95-1.50) | 1.16 (0.95-1.42) | 1.62 (1.13-2.31)b | 1.38 (0.97-1.96)d |
Prior heart failure | 1.21 (1.09-1.33) | 1.28 (1.09-1.51)b | 1.12 (0.96-1.32) | 1.06 (0.75-1.51) | 1.42 (1.10-1.84)b |
CVA | 1.16 (1.04-1.30)c | 1.22 (1.0-1.50)c | 1.05 (0.87-1.25) | 1.41 (1.00-1.99)d | 1.16 (0.88-1.54) |
COPD | 1.15 (1.04-1.27)b | 1.21 (1.02-1.45)c | 0.87 (0.74-1.02)d | 1.28 (0.90-1.83) | 1.23 (0.94-1.60) |
Initial systolic BP | 0.99 (0.99-0.99)b | 0.99 (0.99-1.00)b | 0.99 (0.99-0.99)b | 0.99 (0.99-1.00)b | 0.99 (0.99-0.99)b |
Initial heart rate | 1.01 (1.00-1.01)c | 1.01 (1.00-1.01)b | 1.01 (1.00-1.01)b | 1.01 (1.00-1.01)b | 1.01 (1.00-1.01)b |
Prehospital intubation | 3.93 (3.48-4.44)b | 2.49 (1.91-3.24)b | 2.53 (1.83-3.51)b | 6.91 (3.56-13.44)b | 5.62 (4.12-7.65)b |
Prehospital cardiac arreste | NA | 2.41 (1.82-3.19)b | NA | NA | NA |
Socioeconomic statusf | 0.96 (0.94-0.98)b | 0.94 (0.90-0.98)b | 1.00 (0.96-1.04) | 0.97 (0.89-1.05) | 0.96 (0.90-1.02) |
Abbreviations: BP, blood pressure; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; HR, hazard ratio; NA, not applicable.
HRs represent time-to-death analysis using a Cox regression model. Individual analyses were performed for each etiology.
P < .01.
P < .05.
P < .10.
Prehospital cardiac arrest as determined by the Victorian Ambulance Cardiac Arrest registry was included as a covariate in the model for cardiogenic shock.
Socioeconomic status uses Index of Relative Socioeconomic Disadvantage decile.