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Effect of YB-16 on thermal sensitivity. Subcutaneous systemic injections of capsaicin (2 mg/kg) and YB-16 (6 mg/kg) reduced hotplate sensitivity compared to that of vehicle (one-way ANOVA P = 0.0098). n = 5 cap group; n = 10 other groups. *P = 0.02 and **P = 0.007 Dunnett’s multiple comparison.
