Table 6. Overall Comparison of YB-2, YB-11, YB-16, and Capsaicin.
compound | EC50 (μM) | solubility (g/l00 mL) | pungency RPP |
---|---|---|---|
capsaicin | 0.11 | 0.0013 | 100 |
YB-2a | 0.082 | 2.0 | 17.6 |
YB-11 | 0.012 | 0.0027 | 40.6 |
YB-16 | 0.93 | 0.016 | 13.6 |
YB-2 was tested as a HCl salt; RPP, relative pain-producing potency with capsaicin set to 100.