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. 2022 Jan 25;98(4):e364–e375. doi: 10.1212/WNL.0000000000013080

Figure 5. Postmortem Brain Immunohistochemistry.

Figure 5

Representative histologic staining of postmortem tissue from corpus callosum (CC) of preterm infants. Hematoxylin & eosin (A, B) and synaptophysin (C, D) of preterm infants without (A, C) or with (B, D) post-hemorrhagic hydrocephalus (PHH). Infants with PHH had relatively increased cellular infiltration (B, D) and vacuolation of their cytoplasm to suggest edema (B). Decreased axonal staining in PHH (D) suggests a relatively decreased fiber fraction in comparison to controls (C). The CC is not myelinated at term equivalent.