FIGURE 6.

Increased astrogliosis post-BCAS in cortex. Representative images of GFAP immunostaining to assess the degree of astrogliosis in the superficial brain cortex of WT and Tg-SwDI, sham and BCAS mice. (A,C) In the superficial cortex, BCAS caused increased astrogliosis but was unaffected in Tg-SwDI mice. (B,D) In the hippocampus, there was increased astrogliosis in Tg-SwDI mice but not post-BCAS. * and ^** indicate p < 0.05 and 0.01, respectively. Data are shown as individual data points, mean ± SEM, n = 6–10 per group. Scale bar = 100 μm.