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. 2022 Jan 13;11:802177. doi: 10.3389/fonc.2021.802177

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Copyright © 2022 Hajjaji, Aboulouard, Cardon, Bertin, Robin, Fournier and Salzet

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analyses of the proteins from the clonal proteome associated both with DMFS and OS, showing (A) enrichment, (B) networks analysis, (C) cerebral layout of cellular distribution, and (D) their druggability. In the table, targets with a known drug-target interaction are in dark green, those with a less known interaction are in green, and those with limited data are in yellow. The target class, matching drug name, ATC classification and reported antitumor activity in breast cancer are indicated. *p < 0.05; **p < 0.01.