Table 2.
Prophylactic dose | |
Enoxaparin | 30 to 40 mg SC / <0.7 mg/Kg/24hours 30 to 40 mg SC / <0.4 mg/Kg/12hours |
Unfractionated heparin | 5000 IU SC TID 5000 to 7500 IU SC TID |
Fondaparinux | 2.5 mg SC once daily for 5 to 10 days |
Intermediate dose | |
Enoxaparin | ≥0.4 but ≤0.7 mg/Kg/12hours |
Unfractionated heparin | 5000 IU SC TID 5000 to 7500 IU SC TID |
Therapeutic dose | |
Enoxaparin | ≥0.7 mg/Kg/12 hours ≥0.7 mg/Kg/24 h for patients with CKD >1.4 mg/Kg/24 hours |
Therapeutic Dose Cont. | |
Unfractionated heparin | IV bolus followed by drip, with aPTT guided dose adjustments |
Bivalirudin | IV bolus followed by drip, with ACT guided dose adjustments |
aPTT: activated partial thromboplastin time; ACT: activated clotting time; CKD: chronic kidney disease; IV intravenous; SC: subcutaneous; TID: three time per day.