. 2001 Apr;39(4):1328–1333. doi: 10.1128/JCM.39.4.1328-1333.2001

TABLE 3.

Analysis of differences between methods for MIC determination for 138 positive blood cultures containing yeasts

Antifungal agent and test methods compared	n	Mean difference between methods (log₂ dilutions)	P^a	Limit of 95% CI (log₂ dilution)		No. (%) of indicated type of error
Antifungal agent and test methods compared	n	Mean difference between methods (log₂ dilutions)	P^a	Lower	Upper	Minor	Major
Amphotericin B
DET-24/MD	132	−0.753	0.016	−0.978	−0.528	NA^b	NA
DET-48/MD	138	−0.138	0.000	−0.352	0.076	NA	NA
ET/MD	138	−0.297	0.000	−0.514	−0.080	NA	NA
Flucytosine
DET-24/MD	132	−0.258	0.003	−0.791	0.275	3 (2.3)	0 (0)
DET-48/MD	138	−0.065	0.001	−0.604	0.474	2 (1.4)	0 (0)
ET/MD	138	−0.181	0.001	−0.719	0.357	3 (2.2)	0 (0)
Fluconazole
DET-24/MD	132	−0.356	0.018	−0.957	0.245	4 (3.0)	0 (0)
DET-48/MD	138	0.174	0.003	−0.419	0.767	5 (3.6)	0 (0)
ET/MD	138	−0.167	0.004	−0.772	0.439
Itraconazole
DET-24/MD	132	0.662	0.130	0.074	1.249	24 (18.2)	4 (3.0)
DET-48/MD	138	0.957	0.442	0.373	1.540	23 (16.7)	5 (3.6)
ET/MD	138	0.703	0.150	0.141	1.265	22 (15.9)	6 (4.3)
Ketoconazole
DET-24/MD	132	−0.042	0.001	−0.591	0.506	NA	NA
DET-48/MD	138	0.529	0.053	−0.043	1.101	NA	NA
ET/MD	138	0.065	0.001	−0.502	0.632	NA	NA

A P value of <0.05 indicates that the difference was small.

NA, not applicable.