Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
GSK3 activation is mediated by SGK3 deficiency in regulating podocyte dysfunction. Lack of SGK3 results in decreased phosphorylation of GSK3, thereby activating GSK3. Activation of GSK3 inhibits cell viability and podocin expression, which contributes to podocyte dysfunction.
