Table 5.
Genotype and allelic stratification of eight significant SNPs in chromosome 9 on the ABO gene into the ABO blood group.
| SNP | Blood group | Genotype | Non-critical (n = 341) | Critical (n = 186) | p-value | Allele | Non-critical (n = 341) | Critical (n = 186) | p-value |
|---|---|---|---|---|---|---|---|---|---|
| rs199969472 | A | GG | 46 (48.4%) | 26 (40.0%) | 0.575 | G | 46 (48.4%) | 26 (40.0%) | 0.293 |
| GA | 44 (46.3%) | 35 (53.8%) | A | 49 (51.6%) | 39 (60.0%) | ||||
| AA | 5 (5.3%) | 4 (6.2%) | |||||||
| AB | GG | 11 (47.8%) | 6 (50.0%) | 0.349 | G | 11 (47.8%) | 6 (50.0%) | 0.903 | |
| GA | 12 (52.2%) | 5 (41.7%) | A | 12 (52.2%) | 6 (50.0%) | ||||
| AA | 0 (0.0%) | 1 (8.3%) | |||||||
| B | GG | 69 (89.6%) | 53 (93.0%) | 0.295 | G | 69 (89.6%) | 53 (93.0%) | 0.499 | |
| GA | 8 (10.4%) | 3 (5.3%) | A | 8 (10.4%) | 4 (7.0%) | ||||
| AA | 0 (0.0%) | 1 (1.8%) | |||||||
| O | GG | 130 (89.0%) | 37 (71.2%) | 0.005 | G | 130 (89.0%) | 37 (71.2%) | 0.002 | |
| GA | 15 (10.3%) | 15 (28.8%) | A | 16 (11.0%) | 15 (28.8%) | ||||
| AA | 1 (0.7%) | 0 (0.0%) | |||||||
| rs34266669 | A | CC | 46 (48.4%) | 26 (40.0%) | 0.575 | C | 46 (48.4%) | 26 (40.0%) | 0.293 |
| CT | 44 (46.3%) | 35 (53.8%) | T | 49 (51.6%) | 39 (60.0%) | ||||
| TT | 5 (5.3%) | 4 (6.2%) | |||||||
| AB | CC | 11 (47.8%) | 6 (50.0%) | 0.349 | C | 11 (47.8%) | 6 (50.0%) | 0.903 | |
| CT | 12 (52.2%) | 5 (41.7%) | T | 12 (52.2%) | 6 (50.0%) | ||||
| TT | 0 (0.0%) | 1 (8.3%) | |||||||
| B | CC | 69 (89.6%) | 53 (93.0%) | 0.295 | C | 69 (89.6%) | 53 (93.0%) | 0.499 | |
| CT | 8 (10.4%) | 3 (5.3%) | T | 8 (10.4%) | 4 (7.0%) | ||||
| TT | 0 (0.0%) | 1 (1.8%) | |||||||
| O | CC | 130 (89.0%) | 37 (71.2%) | 0.005 | C | 130 (89.0%) | 37 (71.2%) | 0.002 | |
| CT | 15 (10.3%) | 15 (28.8%) | T | 16 (11.0%) | 15 (28.8%) | ||||
| TT | 1 (0.7%) | 0 (0.0%) | |||||||
| rs76700116 | A | AA | 46 (48.4%) | 26 (40.0%) | 0.575 | A | 46 (48.4%) | 26 (40.0%) | 0.293 |
| AC | 44 (46.3%) | 35 (53.8%) | C | 49 (51.6%) | 39 (60.0%) | ||||
| CC | 5 (5.3%) | 4 (6.2%) | |||||||
| AB | AA | 11 (47.8%) | 6 (50.0%) | 0.349 | A | 11 (47.8%) | 6 (50.0%) | 0.903 | |
| AC | 12 (52.2%) | 5 (41.7%) | C | 12 (52.2%) | 6 (50.0%) | ||||
| CC | 0 (0.0%) | 1 (8.3%) | |||||||
| B | AA | 69 (89.6%) | 53 (93.0%) | 0.295 | A | 69 (89.6%) | 53 (93.0%) | 0.499 | |
| AC | 8 (10.4%) | 3 (5.3%) | C | 8 (10.4%) | 4 (7.0%) | ||||
| CC | 0 (0.0%) | 1 (1.8%) | |||||||
| O | AA | 130 (89.0%) | 37 (71.2%) | 0.005 | A | 130 (89.0%) | 37 (71.2%) | 0.002 | |
| AC | 15 (10.3%) | 15 (28.8%) | C | 16 (11.0%) | 15 (28.8%) | ||||
| CC | 1 (0.7%) | 0 (0.0%) | |||||||
| rs7849280 | A | AA | 46 (48.4%) | 26 (40.0%) | 0.551 | A | 46 (48.4%) | 26 (40.0%) | 0.293 |
| AG | 43 (45.3%) | 35 (53.8%) | G | 49 (51.6%) | 39 (60.0%) | ||||
| GG | 6 (6.3%) | 4 (6.2%) | |||||||
| AB | AA | 11 (47.8%) | 6 (50.0%) | 0.349 | A | 11 (47.8%) | 6 (50.0%) | 0.903 | |
| AG | 12 (52.2%) | 5 (41.7%) | G | 12 (52.2%) | 6 (50.0%) | ||||
| GG | 0 (0.0%) | 1 (8.3%) | |||||||
| B | AA | 69 (89.6%) | 53 (93.0%) | 0.295 | A | 69 (89.6%) | 53 (93.0%) | 0.499 | |
| AG | 8 (10.4%) | 3 (5.3%) | G | 8 (10.4%) | 4 (7.0%) | ||||
| GG | 0 (0.0%) | 1 (1.8%) | |||||||
| O | AA | 130 (89.0%) | 37 (71.2%) | 0.005 | A | 130 (89.0%) | 37 (71.2%) | 0.002 | |
| AG | 15 (10.3%) | 15 (28.8%) | G | 16 (11.0%) | 15 (28.8%) | ||||
| GG | 1 (0.7%) | 0 (0.0%) | |||||||
| rs34039247 | A | AA | 80 (84.2%) | 51 (78.5%) | 0.650 | A | 80 (84.2%) | 51 (78.5%) | 0.354 |
| AC | 14 (14.7%) | 13 (20.0%) | C | 15 (15.8%) | 14 (21.5%) | ||||
| CC | 1 (1.1%) | 0 (0.0%) | |||||||
| AB | AA | 19 (82.6%) | 11 (91.7%) | 0.467 | A | 19 (82.6%) | 11 (91.7%) | 0.467 | |
| AC | 4 (17.4%) | 1 (8.3%) | C | 4 (17.4%) | 1 (8.3%) | ||||
| CC | 0 (0.0%) | 0 (0.0%) | |||||||
| B | AA | 74 (98.7%) | 55 (96.5%) | 0.493 | A | 76 (98.7%) | 55 (96.5%) | 0.393 | |
| AC | 3 (1.3%) | 1 (1.8%) | C | 1 (1.3%) | 2 (3.5%) | ||||
| CC | 0 (0.0%) | 1 (1.8%) | |||||||
| O | AA | 139 (93.2%) | 41 (78.8%) | 0.012 | A | 136 (93.2%) | 41 (78.8%) | 0.004 | |
| AC | 7 (4.8%) | 9 (17.3%) | C | 10 (6.8%) | 11 (21.2%) | ||||
| CC | 3 (2.1%) | 2 (3.8%) | |||||||
| rs10901251 | A | AA | 39 (41.1%) | 25 (38.5%) | 0.597 | A | 39 (41.1%) | 25 (38.5%) | 0.742 |
| AC | 50 (52.6%) | 33 (50.8%) | C | 56 (58.9%) | 40 (51.5%) | ||||
| CC | 6 (6.3%) | 7 (10.8%) | |||||||
| AB | AA | 1 (4.3%) | 0 (0.0%) | 0.740 | A | 1 (4.3%) | 0 (0.0%) | 0.464 | |
| AC | 10 (43.5%) | 6 (50.0%) | C | 22 (95.7%) | 12 (100.0%) | ||||
| CC | 12 (52.2%) | 6 (50.0%) | |||||||
| B | AA | 8 (10.4%) | 2 (3.5%) | 0.320 | A | 8 (10.4%) | 2 (3.5%) | 0.134 | |
| AC | 53 (68.8%) | 43 (75.4%) | C | 69 (89.6%) | 55 (96.5%) | ||||
| CC | 16 (20.8%) | 12 (21.2%) | |||||||
| O | AA | 121 (82.9%) | 36 (69.2%) | 0.107 | A | 121 (82.9%) | 36 (69.2%) | 0.037 | |
| AC | 21 (14.4%) | 14 (26.9%) | C | 25 (17.1%) | 16 (30.8%) | ||||
| CC | 4 (2.7%) | 2 (2.8%) | |||||||
| rs9411475 | A | TT | 47 (49.5%) | 28 (43.1%) | 0.586 | T | 47 (49.5%) | 28 (43.1%) | 0.426 |
| TC | 42 (44.2%) | 34 (52.3%) | C | 48 (50.5%) | 37 (56.9%) | ||||
| CC | 6 (6.3%) | 3 (4.6%) | |||||||
| AB | TT | 10 (43.5%) | 6 (50.0%) | 0.713 | T | 10 (43.5%) | 6 (50.0%) | 0.713 | |
| TC | 13 (56.5%) | 6 (50.0%) | C | 13 (56.5%) | 6 (50.0%) | ||||
| CC | 0 (0.0%) | 0 (0.0%) | |||||||
| B | TT | 73 (94.8%) | 55 (96.5%) | 0.641 | T | 73 (94.8%) | 55 (96.5%) | 0.641 | |
| TC | 4 (5.2%) | 2 (3.5%) | C | 4 (5.2%) | 2 (3.5%) | ||||
| CC | 0 (0.0%) | 0 (0.0%) | |||||||
| O | TT | 129 (88.4%) | 38 (73.1%) | 0.020 | T | 129 (88.4%) | 38 (73.1%) | 0.009 | |
| TC | 16 (11.0%) | 14 (26.9%) | C | 17 (11.6%) | 14 (26.9%) | ||||
| CC | 1 (0.7%) | 0 (0.0%) | |||||||
| rs13291798 | A | AA | 83 (87.4%) | 53 (81.5%) | 0.348 | A | 83 (87.4%) | 53 (81.5%) | 0.310 |
| AG | 11 (11.6%) | 12 (18.5%) | G | 12 (12.6%) | 12 (18.5%) | ||||
| GG | 1 (1.1%) | 0 (0.0%) | |||||||
| AB | AA | 20 (87.0%) | 10 (83.3%) | 0.771 | A | 20 (87.0%) | 10 (83.3%) | 0.771 | |
| AG | 3 (13.0%) | 2 (16.7%) | G | 3 (13.0%) | 2 (16.7%) | ||||
| GG | 0 (0.0%) | 0 (0.0%) | |||||||
| B | AA | 74 (96.1%) | 56 (98.2%) | 0.471 | A | 74 (96.1%) | 56 (98.2%) | 0.471 | |
| AG | 3 (3.9%) | 1 (1.8%) | G | 3 (3.9%) | 1 (1.8%) | ||||
| GG | 0 (0.0%) | 0 (0.0%) | |||||||
| O | AA | 139 (95.2%) | 44 (84.6%) | 0.021 | A | 139 (95.2%) | 44 (84.6%) | 0.013 | |
| AG | 6 (4.1%) | 8 (15.4%) | G | 7 (4.8%) | 8 (15.4%) | ||||
| GG | 1 (0.7%) | 0 (0.0%) |