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. 2022 Jan 13;9:801321. doi: 10.3389/fped.2021.801321

Table 1.

Risk factors of first febrile seizure.

Risk factor Odds ratio (95% CI)
Family history of febrile seizures* 4.5 (2.09–9.83) (23)
Family history of afebrile seizures and epilepsy 2.6 (0.5–14.3) (15)
Developmental delay* 4.9 (1.55–15.5) (23)
Viral infection* 3.5 (2.2–5.6) for respiratory or enteric virus detection in children with febrile seizures compared to healthy controls (25).
High fever temperature* 1.8 (1.3–2.5) for every degree above 101°F (15).
Maternal smoking 3.0 (1.0–9.0) if child exposed to any perinatal smoking (15).
Neonatal discharge >28 days 5.6 OR (1.55–20.5) (23)
Low serum zinc* 1.5 (1.1–2.3) (21)
Low serum iron* 1.84 (1.02–3.31) (22)
*

Denotes statistically significant risk factors.