TABLE 3.
Normalized protein abundance, mean fold- change, and p value of the twelve proteins found to be significantly different between platelet function groups
| Normalized protein abundance |
||||
|---|---|---|---|---|
| Protein | High platelet function (n = 12) | Low platelet function (n = 12) | Mean fold-change (Low vs. High Platelet Function Groups) | p value |
| Gelsolin | 1.48E + 7 (1.32E + 7– 1.71E + 7) | 9.70E + 6 (8.27E + 6– 1.19E + 7) | 0.68 | .002 |
| Transketolase | 9.36E + 3 (7.67E + 3– 1.76E + 4) | 2.86E + 4 (1.35E + 4– 4.15E + 4) | 3.68 | .003 |
| Protein S100-A8 | 2.64E + 4 (8.29E + 3– 2.87E + 4) | 4.60E + 4 (2.83E + 4– 6.26E + 4) | 5.16 | .006 |
| Histone H4 | 8.47E + 3 (7.62E + 3– 7.10E + 4) | 5.72E + 4 (7.20E + 3– 1.50E + 5) | 16.10 | .007 |
| Histidine-rich glycoprotein | 8.30E + 6 (7.11E + 6– 9.45E + 6) | 5.00E + 6 (3.50E + 6– 6.04E + 6) | 0.64 | .008 |
| Protein S100- A9 | 4.07E + 4 (2.78E + 4– 5.11E + 4) | 5.83E + 4 (4.42E + 4– 1.17E + 5) | 5.20 | .012 |
| Coagulation factor XIII B chain | 1.61E + 6 (1.22E + 6– 1.81E + 6) | 1.09E + 6 (9.70E + 5– 1.30E + 6) | 0.74 | .020 |
| Apolipoprotein A-IV | 3.28E + 7 (2.46E + 7– 4.04E + 7) | 2.30E + 7 (1.67E + 7– 2.58E + 7) | 0.76 | .024 |
| Alpha- enolase | 4.15E + 4 (1.77E + 4– 1.03E + 5) | 1.02E + 5 (4.59E + 4– 1.32E + 5) | 3.36 | .024 |
| Heat shock protein 90- alpha | 4.08E + 3 (3.10E + 3– 1.25E + 4) | 1.41E + 4 (6.40E + 3– 2.79E + 4) | 3.82 | .045 |
| Alpha−2-HS-glycoprotein | 3.68E + 7 (3.06E + 7– 4.26E + 7) | 2.83E + 7 (2.34E + 7– 3.34E + 7) | 0.79 | .045 |
| Neutrophil gelatinase-associated lipocalin | 1.36E + 4 (7.72E + 3– 2.06E + 4) | 3.44E + 4 (1.42E + 4– 5.99E + 4) | 2.24 | .045 |
Normalized protein abundance reported as median (IQR).
p values obtained by Wilcoxon rank- sum test.