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. 2022 Jan 27:10.2217/fon-2021-1248. doi: 10.2217/fon-2021-1248

Table 1. Characteristics of study participants.

Characteristic Patient group (n = 776) Control group (n = 715) p-value
  n (%) n (%)  
Age, median (range) 64 (20–88) 50 (21–94) <0.001
Age (years)
  <60
  ≥60

291
485

37.5
62.5

614
101

85.9
14.1
<0.001
Sex
  Female
  Male

433
343

55.8
44.2

398
317

55.7
44.3
0.958
BMI, median (range) 27.1 (16–48) 26.1 (18–40) 0.943
BMI
  <25 kg/m2
  ≥25 kg/m2

187
422

30.7
69.3

118
269

30.5
69.5
0.943
Smoking
  No
  Ex-smoker
  Yes

436
165
135

59.3
22.4
18.3

428
16
149

72.2
2.7
25.1
<0.001
Diabetes mellitus
  No
  Yes

635
141

81.8
18.2

666
49

93.1
6.9
<0.001
Hypertension
  No
  Yes

513
263

66.1
33.9

616
99

86.2
13.8
<0.001
Coronary disease
  No
  Yes

710
66

91.5
8.5

698
17

97.6
2.4
<0.001
Chronic renal failure
  No
  Yes

759
17

97.8
2.2

714
1

99.9
0.1
<0.001
Chronic liver disease
  No
  Yes

761
15

98.1
1.9

709
6

99.2
0.8
0.081
Rheumatological disease
  No
  Yes

766
10

98.7
1.3

707
8

98.9
1.1
0.816
Psychiatric disease
  No
  Yes

762
14

98.2
1.8

713
2

99.7
0.3
0.004
Respiratory disease
  No
  Yes

741
35

95.5
4.5

703
12

98.3
1.7
0.002
Other
  No
  Yes

731
45

94.2
5.8

686
29

95.9
4.1
0.152

Statistically significant results.