Table 5.

Summary of regression analyses showing inflammatory moderation of sex effects on verbal memory.

	IL-1β
		RAVLT Total					RAVLT Delay
Time 1	p < 0.01		F = 5.12			p < 0.01		F = 3.63
	β	p	t	95% CI		β	p	t	95% CI
Sex	15.59	<.01	4.14	−31.08	33.82	5.72	<.01	3.75	2.69	8.75
Log IL-1β	30.06	0.11	1.63	8.11	23.07	14.95	0.05	2.03	0.31	29.6
Sex × IL-1β	−27.77	0.02	−2.34	−6.44	66.56	−11.91	0.01	−2.49	−21.38	−2.43
Age	−0.15	0.3	−1.05	−51.31	−4.22	−0.07	0.27	−1.05	−0.18	0.05
Education	0.82	0.03	2.21	0.09	1.56	0.19	0.21	1.26	−0.11	0.49
BMI	0.38	0.1	1.66	−0.08	0.84	0.06	0.57	0.56	−0.14	0.26
	RAVLT Total					RAVLT Delay
Time 2	p < 0.01		F = 3.62			p = 0.10		F = 1.86
	β	p	t	95% CI		β	p	t	95% CI
Sex	11.62	0.02	2.32	1.64	21.59	6.23	<.01	3	2.07	10.37
Log IL-1β	5.78	0.8	0.25	−39.69	51.24	19.06	0.04	2.1	0.93	37.19
Sex × IL-1β	−7.28	0.64	−0.47	−37.98	23.41	−14.18	0.03	−2.19	−27.09	−1.27
Age	−0.43	0.03	−2.23	−0.81	−0.06	−0.03	0.7	−0.38	−0.17	0.12
Education	0.69	0.18	1.35	−0.33	1.71	0.13	0.53	0.64	−0.28	0.53
BMI	0.84	0.02	2.44	0.15	1.52	0.13	0.28	0.28	−0.11	0.36
	IL-6
	RAVLT Total					RAVLT Delay
Time 1	p < 0.01		F = 3.63			p < 0.01		F = 3.12
	β	p	t	95% CI		β	p	t	95% CI
Sex	12.49	0.09	1.74	−1.8	23.78	5.82	0.07	1.81	−0.55	12.2
Log IL-6	7.72	0.68	0.42	−28.82	44.25	9.52	0.22	1.22	−5.94	24.97
Sex × IL-6	−5.83	0.64	−0.47	−30.62	18.95	−5.09	0.37	−0.9	−16.26	6.09
Age	−0.21	0.18	−1.36	−0.52	0.1	−0.11	0.09	−1.73	−0.23	0.02
Education	0.71	0.08	1.79	−0.08	1.5	0.13	0.83	0.83	−0.19	0.45
BMI	0.41	0.11	1.61	−0.1	0.92	0.05	0.69	0.4	−0.18	0.27
	RAVLT Total					RAVLT Delay
Time 2	p < 0.01		F = 3.58			p = 0.01		F = 4.27
	β	p	t	95% CI		β	p	t	95% CI
Sex	9.9	0.29	1.07	−8.58	28.37	10.62	<0.01	2.91	3.32	17.92
Log IL-6	25.08	0.25	1.16	−18.22	68.38	22.77	<0.01	2.73	6.13	39.41
Sex × IL-6	−5.63	0.71	−0.37	−36.01	24.75	−15.32	0.02	−2.46	−27.77	−2.88
Age	−0.59	0.004	−3.03	−0.97	−0.2	−0.07	0.31	−1.02	−0.022	0.07
Education	1.01	0.06	1.95	−0.03	2.05	0.13	0.49	0.7	−0.25	0.51
BMI	0.53	0.11	1.61	−0.13	1.18	0.09	0.47	0.73	−0.15	0.33
	TNF-α
	RAVLT Total					RAVLT Delay
Time 1	p < 0.01		F = 3.81			p < 0.01		F = 3.63
	β	p	t	95% CI		β	p	t	95% CI
Sex	15.06	0.13	1.53	−4.46	34.57	1.6	0.68	0.42	−6.01	9.2
TNFα	0.15	0.42	0.82	−0.21	0.51	0.03	0.7	0.38	−0.11	0.17
Sex × TNFα	−0.07	0.54	−0.61	−0.31	0.16	0.02	0.73	0.35	−0.08	0.11
Age	−0.3	0.06	−1.89	−0.61	0.06	−0.15	0.02	−2.36	−0.27	−0.02
Education	0.83	0.04	2.12	0.05	1.6	0.25	0.12	1.56	−0.07	−0.02
BMI	0.52	0.07	1.83	−0.04	1.08	0.1	0.4	0.84	−0.13	0.32
	RAVLT Total					RAVLT Delay
Time 2	p < 0.01		F = 4.00			p = 0.06		F = 2.15
	β	p	t	95% CI		β	p	t	95% CI
Sex	12.2	0.31	1.03	−11.52	35.91	0.77	0.87	0.65	−8.56	10.1
TNFα	0.2	0.33	0.98	−0.21	0.62	−0.001	0.99	−0.02	−0.16	0.16
Sex × TNFα	−0.04	0.8	−0.25	−0.32	0.25	0.02	0.69	0.4	−0.09	0.13
Age	−0.55	<0.01	−2.79	−0.94	−0.16	−0.15	0.05	−2.05	−0.3	−0.003
Education	1.21	0.02	2.33	0.17	2.26	0.28	0.17	1.4	−0.12	0.67
BMI	0.88	0.01	2.66	0.22	1.54	0.11	0.38	0.89	−0.14	0.36

Note: BMI: body mass index; IL-1β: interleukin-1β; IL-6: interleukin-6; RAVLT: Rey Auditory Verbal Learning Test; TNF-α: tumor necrosis factor-α.