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. 2021 Aug 25;6(2):361–373. doi: 10.1002/hep4.1810

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© 2021 The Authors. Hepatology Communications published by Wiley Periodicals LLC on behalf of American Association for the Study of Liver Diseases

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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FIG. 5 — PK of serum APAP‐protein adducts in subjects with cirrhosis and noncirrhotic controls. Serum APAP‐protein adducts were measured in serial blood samples collected after the final dose of APAP on day 5 using HPLC‐EC. (A) Starting day‐5 APAP‐protein adducts in serum. (B) APAP‐protein adducts Cmax on day 5. (C) Half‐life of APAP‐protein adducts. (D) AUC of APAP‐protein adducts. Data are expressed as mean ± SE. Dots show individual data points as described in the text. *P < 0.05 versus noncirrhotic controls.