FIG. 5.

The combination of BAY41 and IFN‐α reduces HBV‐DNA levels more effectively than BAY41 or IFN‐α monotherapy. (A‐C) HBV‐infected PHHs were treated with BAY41 alone, IFN‐α alone, or their combination for indicated days. (A) Schematic of the experimental procedure. (B) WST assay at indicated days after treatment (n = 6). Each value was compared to that in the untreated control. (C) cccDNA levels and HBV‐DNA, HBsAg, and HBeAg levels in the culture supernatants after 2 days or 12 days of treatment (n = 4). The data are shown as the mean ± SEM. *P < 0.05.