TABLE 2.
Cox Regression Survival Model in Full Cohort and Liver Disease Etiology Subsets: Effect of TL (as continuous variable) and Between TL Quartiles (Compared With Longest Quartile) on All‐Cause Mortality
| TL Analysis Cohort (n = 7,069) | Characterized Liver Disease (n = 2,071) | MetS‐Related Liver Disease (n = 1,203) | Alcohol‐Associated Liver Disease (n = 713) | |||||
|---|---|---|---|---|---|---|---|---|
| Deaths | HR (95% CI) | Deaths | HR (95% CI) | Deaths | HR (95% CI) | Deaths | HR (95% CI) | |
| All‐Cause Mortality | ||||||||
| TL (kbp) | 1630 | 1.20 [1.04‐1.38] | 516 | 1.22 [0.99‐1.51] | 313 | 1.26 [0.96‐1.67] | 151 | 1.13 [0.77‐1.68] |
| TL quartiles | ||||||||
| First quartile | 468 | 1.24 [1.02‐1.50] | 157 | 1.22 [0.91‐1.63] | 91 | 1.21 [0.80‐1.81] | 46 | 1.28 [0.81‐2.04] |
| Second quartile | 386 | 1.07 [0.90‐1.27] | 116 | 1.00 [0.75‐1.35] | 68 | 0.95 [0.64‐1.42] | 36 | 1.08 [0.69‐1.68] |
| Third quartile | 414 | 1.11 [0.92‐1.35] | 117 | 0.99 [0.69‐1.43] | 74 | 1.02 [0.58‐1.78] | 34 | 1.10 [0.63‐1.92] |
| Fourth quartile (longest) | 362 | 1.00 | 126 | 1.00 | 80 | 1.00 | 35 | 1.00 |
All models adjusted for age, and dummy variables adjusted for female sex, race/ethnicity, smoking history, MetS, and presence of advanced fibrosis.