Table 1.

Representative categories and linked data elements

Source	Category	Representative elements
Cancer Registry	Demographics	age_at_dx, sex, marital_status_at_dx, race, nhia, napiia, county_at_dx, etc
	Vital information	vital_status, date_of_death, primary_cause
	Tumor information	Primary_site, laterality, grade, diagnosis_confirmation
	Tumor extension and metastasis	cs_extension, cs_tumor_size, cs_lymph_nodes, cs_mets_at_dx
	Pathology info and tumor staging	histology_icdo3, behavior_icdo3, clinical and pathology staging in AJCC 6, 7, 8 and SEER staging
	Site-specific data	cs_site_specific factors
	Tumor treatments	Surgical, radiation, hormone, BRM, and other cancer treatment information
Imaging	Pathology images	Digitized representative diagnostic slides in Olympus (.vsi) and Philips (.svs?) whole slide image formats, including image metadata such as imaging device, optical settings and configuration, specimen staining, etc.
	Computational imaging signatures	Tumor-infiltrating lymphocytes; tumor pattern segmentation; tumor and stromal nuclei segmentation; spatial and spectral signatures