Table 1:
MRI imaging modality, advantage at 7T and detected epileptogenic abnormalities
| Technique | Advantage at 7T | Abnormalities detected and imaging markers |
|---|---|---|
| T1 | Increased SNR enables higher isotropic resolution | Cortical, migrational and hippocampal abnormalities. Hippocampal subfield and thalamic subnuclei volumetrics |
| T2 | Increased SNR and enhanced contrast results in increased conspicuity of lesions | Cortical abnormalities (dysplasias, malformations, heterotopias), hippocampal sclerosis, lesions. Hippocampal subfield and thalamic subnuclei volumetrics |
| SWI | Increased sensitivity to susceptibility effects and venous anomalies | Vascular lesions, hypervascularity, and cavernomas, associated with or acting as seizure source |
| MRSI | Increased SNR and spectral separation. | Neuronal loss detected through NAA/Cr levels. |
| dMRI | Increased SNR. Hippocampal subfield- specific connectivity may be performed | Abnormal structural connectivity underlying seizure networks. Hippocampal subfield-specific tract density. |
| fMRI | Increased SNR and BOLD contrast | Abnormal functional connectivity in seizure networks. |