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. 2022 Jan 25;60(1):212–224. doi: 10.1080/13880209.2022.2025860

Figure 2.

Figure 2.

Differences in bone mineral density (BMD), lean body mass (LBM), and fat mass (FM) before hippocampal amyloid-β infusion and at the end of the intervention. Amyloid-β(25–35) infused rats were fed a high-fat diet containing dextrin (AD-CON group), the water extract of Cassiae Semen (AD-CS group), or the water extract of Forsythiae Fructus (AD-FF) for 49 days. Amyloid-β(35–25) infused rats were fed a high-fat diet containing dextrin (CON group). Before hippocampal amyloid-β infusion and at the end of the intervention, body composition was measured by DEXA, and the differences of BMD, LMD, and FM were calculated. (A) Differences between before and after treatments in the lumbar spine and femur BMD. (B) Differences between before and after treatment in hip and leg LBM. (C) Differences between before and after treatment in abdominal and leg FM. Bars and error bars represent the means ± standard deviations (n = 10). *Significantly different from the AD-CON by Tukey test at p < 0.05. †Significantly different from the CON by Tukey test at p < 0.05.