TABLE 3.
Percentages of individuals with serum antibodies to recombinant or synthetic Chlamydia antigens as determined by ELISA
Antigen (source) | Serum antibody response | % of patients with acute C. trachomatis urogenital infection (n = 45) | % of healthy blood donors (n = 31)a | Statistical analysis (chi-square test) between both groupsb |
---|---|---|---|---|
LPS (Medac) | IgG | 84 | 52 | 9.62; P = 0.0019 |
IgM | 9 | 3 | NS | |
IgA | 62 | 23 | 11.61; P = 0.0007 | |
MOMP (Labsystems) | IgG | 58 | 32 | 4.80; P = 0.029 |
IgA | 47 | 16 | 7.61; P = 0.0058 | |
Recombinant proteins prepared in our laboratory | ||||
hsp70 | IgG | 29 | 17 | NS |
IgA | 2 | 0 | NS | |
hsp60 | IgG | 62 | 20 | 13.64; P = 0.0002 |
IgA | 24 | 13 | NS | |
pgp3 | IgG | 53 | 20 | 8.87; P = 0.0029 |
IgA | 9 | 3 | NS | |
MIP | IgG | 20 | 7 | NS |
IgA | 0 | 0 | NS | |
hsp10 | IgG | 2 | 3 | NS |
IgA | 2 | 0 | NS |
Only 30 healthy blood donors were tested for serum antibodies to recombinant proteins.
NS, not significant.