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. 2022 Jan 27;17(1):e0262751. doi: 10.1371/journal.pone.0262751

Fig 1.

Fig 1

A: Workflow of the bioinformatic analysis. B: Using the protein-protein interaction STRING database, we queried our top 50 upregulated genes (sorted by LogFC). The network edges indicate both functional and physical protein associations, the line thickness represents the confidence, it indicates the strength of data support with a minimum required interaction score of 0.9 (most strict confidence filter). Three modules (a: interferon anti-viral proteins, b: interferon-induced chemokines, c: TNF and inflammatory cytokines) are encircled.