Figure 3.

CBSCs increase fibroblasts and decrease apoptosis in vivo 7 days after MI. Representative confocal images (A) and quantification (B) of immunofluorescent staining for Vimentin, DAPI, and cardiac troponin I in swine myocardium 7 days after MI. Representative images of terminal deoxynucleotidyl transferase dUTP nuck end labeling (TUNEL), DAPI, and Galectin-3 staining in the infarct zone of swine myocardium 7 days after MI (C) and their quantification (D–F). n = 4 for vehicle, n = 6 for CBSC for all figures. Scale bar = 25 µm. White arrows indicate TUNEL⁺/DAPI⁺ cells. Staining for Galectin-3 and TUNEL was performed and analyzed concurrently from the same images. CBSCs, cortical bone stem cells; MI, myocardial infarction.