Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 20;321(4):H684–H701. doi: 10.1152/ajpheart.00304.2021

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 the American Physiological Society.

PMC Copyright notice

Figure 5. — A: CBSC-treated macrophages display a unique transcriptome. Principal component analysis of CBSC, M1 (50 ng/mL LPS), M2a (40 ng/mL IL-4), M2c (40 ng/mL IL-10), and M0 (no treatment) macrophages; principal components 1 and 2 represent 64% of total variance. B: heatmap of Pearson’s correlation coefficients between all groups. C–E: volcano plots of fold change vs. −log(P value) representing differentially expressed genes (DEGs) in CBSCs vs. M2a, M2c, and M0 macrophages. F: log₂(fold change) of specific M2a- and M2c-related genes with adjusted P value in bar; values derived from CBSC vs. M2c for M2c genes, CBSC vs. M2a for M2a genes. G: Venn diagram showing DEGs and common genes between M2c, M2a, and CBSCs vs. M0 control macrophages. H: gene ontology enrichment analysis and ranking system based on DEGs of CBSC vs. M0 control. n = 4 for all groups. CBSCs, cortical bone stem cells.