Table 4.

C-indexes and corresponding 95% CIs of pre-radiomics model, delta-radiomics model and RECIST model in predicting PFS and OS for primary and validation cohorts

Model		PFS Prediction		OS Prediction
		C-index	95% CI	C-index	95% CI
Primary Dataset	preRadiomics Model	0.61 ± 0.03	[0.55, 0.67]	0.60 ± 0.04	[0.52, 0.67]
	∆Radiomics Model	0.62 ± 0.03	[0.57, 0.67]	0.61 ± 0.03	[0.54, 0.67]
	RECIST Model	0.56 ± 0.02	[0.52, 0.61]	0.57 ± 0.02	[0.52, 0.62]
Validation Dataset 1	preRadiomics Model	0.51 ± 0.05	[0.42, 0.59]	0.59 ± 0.05	[0.50, 0.69]
	∆Radiomics Model	0.63 ± 0.04	[0.56, 0.70]	0.60 ± 0.04	[0.52, 0.68]
	RECIST Model	0.56 ± 0.03	[0.50, 0.61]	0.54 ± 0.03	[0.49, 0.59]
Validation Dataset 2	preRadiomics Model	0.51 ± 0.04	[0.43, 0.60]	0.61 ± 0.05	[0.52, 0.69]
	∆Radiomics Model	0.64 ± 0.04	[0.55, 0.72]	0.61 ± 0.05	[0.52, 0.71]
	RECIST Model	0.64 ± 0.04	[0.57, 0.72]	0.53 ± 0.05	[0.42, 0.63]