Table 1. Common and uncommon mediastinal sarcomas.

More common mediastinal sarcomas

Synovial sarcoma

Well-differentiated liposarcoma

Dedifferentiated liposarcoma

Malignant peripheral nerve sheath tumor

Ewing sarcoma

Leiomyosarcoma

SMARCA4-deficient thoracic sarcoma

Solitary fibrous tumor^

Less common mediastinal sarcomas

Rhabdomyosarcoma

Clear cell sarcoma

Low-grade fibromyxoid sarcoma

Myxoid liposarcoma

Alveolar soft part sarcoma

Epithelioid hemangioendothelioma

Epithelioid sarcoma

Extraskeletal myxoid chondrosarcoma

Mesenchymal chondrosarcoma

Extrarenal rhabdoid tumor

Malignant pecoma

Follicular dendritic cell sarcoma

Angiosarcoma*

Chondrosarcoma

Osteosarcoma

Chordoma

Various undifferentiated sarcomas

^{^}, solitary fibrous tumor is generally not included under the category of “sarcoma” but is included here due to its frequent occurrence and potential for aggressive/malignant behavior. *, the majority of angiosarcomas of the mediastinum have been reported in studies in which cardiac tumors were included, primary mediastinal angiosarcoma not associated with cardiac tissue is exceedingly rare.