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. 2021 Oct 17;20(23):2507–2518. doi: 10.1080/15384101.2021.1991122

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Figure 2. — METTL3 induced LIFR-AS1 m⁶A to enhance ItsmRNA stability in PC

(a) The correlation the METTL3 and LIFR-AS1 in PC based on GEPIA database. (b, c) qRT-PCR analysis of the level of METTL3 and LIFR-AS1 in indicated PC cell lines. (d) Identify the specific m⁶A methylation loci of LIFR-AS1 by SRAMP website. (e) m⁶A level in LIFR-AS1 in PANC1 and Mia-capa cells with sh-NC or sh-METTL3 line by m⁶A-qPCR. (f) qRT-PCR analysis of LIFR-AS1 mRNA relative to ACTIN in indicated treated PC. *P < 0.05; **P < 0.01; ***P < 0.001; P > 0.05.