Figure 7.

ST2-CM enhanced proliferation and invasion of PC3 and DU145 cells. ST2 cells were treated with exosomes derived from PC3 and DU145 with knockdown of AY927529 or overexpression of AY927529 for 48 h, ST2-CM was collected, and then PC3 and DU145 cells were treated with ST2-CM. CCK-8, transwell assay and flow cytometry assays were uesd to detect proliferation (a and b), invasion (c and d) and apoptosis (e and f) of PC3 and DU145 cells. *P < 0.05 compared with PC3-pcDNA3.1-Exo group, PC3-scramble-Exo group, DU145-pcDNA3.1-Exo group or DU145-scramble-Exo group; **P < 0.01 compared with PC3-scramble-Exo or DU145-scramble-Exo group. N = 4, data were expressed as mean ± SEM; Student’s t test or one-way ANOVA was used for analyzing data