Table 1.
Baseline Characteristics for Patients With Stenotrophomonas maltophilia Infection
| Characteristic | Levofloxacin | TMP -SMX |
|---|---|---|
| (n = 823) | (n = 758) | |
| Patient-level factors | ||
| Admission year | ||
| 2005–2010 | 204 (24.8) | 197 (26.0) |
| 2011–2013 | 208 (25.3) | 208 (27.4) |
| 2014–2015 | 234 (28.4) | 192 (25.3) |
| 2016–2017 | 177 (21.5) | 161 (21.2) |
| Age, y | ||
| 18–44 | 138 (16.8) | 239 (31.5) |
| 45–64 | 247 (30.0) | 203 (26.8) |
| 65–74 | 215 (26.1) | 174 (23.0) |
| ≥75 | 223 (27.1) | 142 (18.7) |
| Sex | ||
| Female | 362 (44.0) | 327 (43.1) |
| Male | 461 (56.0) | 431 (56.9) |
| Race | ||
| Black | 116 (14.1) | 143 (18.9) |
| White | 637 (77.4) | 505 (66.6) |
| Othera | 70 (8.5) | 110 (14.5) |
| Infection site | ||
| Bloodb | 99 (12.0) | 64 (8.4) |
| Respiratory | 724 (88.0) | 694 (91.6) |
| SOFA scorec, median (IQR) | 1.0 (0.0–4.0) | 2.0 (0.0–4.0) |
| Mechanical ventilationd | 87 (10.6) | 78 (10.3) |
| Polymicrobial infection | 343 (41.7) | 315 (41.6) |
| Polymicrobial infection receiving treatment | 165 (20.0) | 178 (23.5) |
| ICU admissione | 215 (26.1) | 237 (31.3) |
| Therapy initiated empirically | 82 (10.0) | 7 (0.9) |
| Pneumonia diagnosisf | 166 (20.2) | 141 (18.6) |
| Immunocompromised | 8 (1.0) | 13 (1.7) |
| Vasopressor administrationg | 89 (10.8) | 87 (11.5) |
| Elixhauser score, median (IQR) | 2.0 (0.0–4.0) | 2.0 (0.0–5.0) |
| Length of stay, median (IQR) | 10.0 (5.0–21.0) | 17.0 (9.0–31.8) |
| Discharge to hospice | 38 (4.6) | 26 (3.4) |
| In-hospital mortality | 87 (10.6) | 108 (14.2) |
| Total mortality | 125 (15.2) | 134 (17.7) |
| Hospital-level factors | ||
| Teaching facility | 506 (63.8) | 473 (67.4) |
| Bed capacity | ||
| >100 | 81 (9.8) | 90 (11.9) |
| 100–199 | 142 (17.3) | 81 (10.7) |
| 200–299 | 145 (17.6) | 129 (17.0) |
| 300–499 | 292 (35.5) | 262 (34.6) |
| ≥500 | 163 (19.8) | 196 (25.9) |
| Urban location | 718 (87.2) | 605 (79.8) |
| Census region | ||
| Midwest | 181 (22.0) | 196 (25.9) |
| Northeast | 156 (19.0) | 146 (19.3) |
| South | 350 (42.5) | 278 (36.7) |
| West | 136 (16.5) | 138 (18.2) |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: ICU, intensive care unit; IQR, interquartile range; SOFA, Sequential Organ Failure Assessment; TMP-SMX, trimethoprim-sulfamethoxazole.
Includes Asian, Pacific Islander, biracial, Hispanic, Native American, other, and unknown.
Encounters with both blood and respiratory sites of infection were categorized as blood infections.
On day index culture was collected.
Day –1 to +2 where culture is collected.
Culture was drawn in ICU setting.
Presence of the International Classification of Diseases (ICD), Ninth Revision diagnosis codes 481, 485, 486, 514; or ICD, Tenth Revision diagnosis codes J18.0, J18.1, J18.2, J18.8, J18.9.
Day –1 to day +2 day index culture was collected.