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Half-maximal inhibitory concentration (EC50) against P. falciparum 3D7, cytotoxicity against HepG2 and selectivity index
| Compound | EC503D7 (μM) ± SD |
IC50HepG2 (μM) |
Selectivity Index IC50 HepG2/ EC50Pf3D7 |
|---|---|---|---|
 |
5.9 ± 0.7 | >25 | >4 |
 |
8 ± 2 | 81 | 10 |
| Artesunate | 0.013 ± 0.006 | ------ | ---- |
Values represent the mean ± SD (n = 2)
