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. 2022 Jan 28;33(2):571–600. doi: 10.1007/s11224-021-01871-2

Table 10.

Protein–ligand binding energies of known medicines and four DKC ligands were compared using MVD with two distinct PDB IDs

3ERT 3S79
Ligand Energy, kcal/mol or MolDock score Existing drug Energy, kcal/mol or MolDock score Ligand Energy, kcal/mol or MolDock score Existing drugs Energy, kcal/mol or MolDock score
DKC-1 −125.271 Tamoxifen  −131.909 DKC-1 −98.215 Anastrozole −107.965
DKC-10 −204.461 DKC-10 −201.613 Exemestane −92.7947
DKC-20 −177.278 DKC-20 −131.397 Letrozole −108.904
DKC-21 −161.958 DKC-21 −123.724