TABLE 3.
Murine models of endometriosis: surgical injection method.
| Strain | Induction age | D:R | Induction tissue | Donor primed | Rec. ovex’ed | E2 | Tissue amount given | Stripped EM | Suspended uterine material | References |
| C57BL/6 | D: 22–24 d R: 2–4 mo | 1:1 | Uterine fragments | PMSG | N | N | Ten 1 mm3 pieces | Y | Saline | Alali et al., 2020 |
| C57BL/6J Ri | NM | NM | DT | E2 and P4 | Y | Y | Ten biopsies | Y | NA | Peterse et al., 2018 |
| C57BL/6-TG (UBC-GFP), WT | 6–8 wk | 1:1 | UHs | PMSG | Y/N | Y | One 1.5 mm piece | Y | PBS | Jones et al., 2018 |
| D: αERKO, C57BL/6-TG (GFP), IL6-KO R: αERKO, C57BL/6, IL6-KO | 2–6 mo | 1:1 | UHs | PMSG | Y | Y | 100 mg minced | Y | PBS | Burns et al., 2018 |
| CD-1 | 6–8 wk | 1:2 | minced UH | PMSG | Y | Y | NM | Y | HBSS | Li et al., 2016 |
| PR(Cre1) + Ptens(fl+), Ptens(fl+) | 8 wk | Auto | minced UH | E2 | Y | Y | 60 mg | N | Eagle’s basal medium | Kim et al., 2014 |
| D: αERKO, βERKO, C57BL/6 R: αERKO, βERKO, C57BL/6 | NM | 1:1 except αERKO 5:1 | minced UH | PMSG | Y | Y | 100 mg | N | PBS | Burns et al., 2012 |
| C57BL/6 FVB/n | 6–8 wk | 1:1 | minced UH | E2 | Y | Y | One uterus | Y | Saline | Dabrosin et al., 2002 |
Ovex, ovariectomy; EM, endometrium; E2, estrogen; P4, progesterone; D, donor; R, recipient; auto, autotransplantation of self-tissue; UH, uterine horn; DT, decidualized tissue; N, no; Y, yes; NM, not mentioned; NA, not applicable; h, hours; d, days; wk, weeks; mo, month; PMSG, pregnant mare serum gonadotrophin; PBS, phosphate buffered saline; HBSS, Hank’s buffered saline solution.