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Paeonol reduced protein levels of pro-inflammatory cytokines in the serum of AEW mice. (A–C) Administration of paeonol decreased the levels of IL-1β (A), IL-4 (B), IL-6 (C) in the serum of AEW-induced mice. Data were expressed as mean ± SEM. # p < 0.05, ## p < 0.01, #### p < 0.0001, compared to the blank group; ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗ p < 0.0001, compared to the AEW model group (n = 4–7 each group).
