Fig. 2.

Median production and stability ratios for most- and least-stable same-gene isoforms are inversely related in YPD medium. Three classes of most- and least-stable isoform pairs are considered, based on whether the downstream isoform is more stable, less stable, or comparably stable to the upstream isoform. For each group, distributions of relative production rate ratios (purple boxes) and relative steady state ratios (at t = 0; blue boxes) are shown alongside the half-life ratio of the same isoforms (gold boxes). Ratios are plotted as log₂ downstream/upstream isoform values. Data (10) are tabulated in SI Appendix.