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. 2021 Nov 4;46(2):437–440. doi: 10.1038/s41366-021-00995-z

Table 2.

Mean T/S ratio and telomere length in base pairs for body composition phenotypes, based on four-phenotype and TrFM/ASM model classifications.

Unadjusted Adjusted
Mean T/S ratioa Telomere length (base pairs) Mean T/S ratioa Telomere length (base pairs)
Mean 95% CI Mean 95% CI P value Mean 95% CI Mean 95% CI P value
BMI
Normal weight (reference) 1.10 1.07–1.13 5930 5851–6009 1.06 1.03–1.09 5829 5747–5911
Overweight 1.05 1.02–1.09 5813 5729–5897 0.003 1.04 1.00–1.08 5790 5698–5883 0.22
Obesity 1.04 1.01–1.07 5780 5701–5859 <0.001 1.04 1.01–1.07 5777 5705–5850 0.07
Four-phenotype model classificationb
LA-HM (reference) 1.08 1.05–1.12 5902 5815–5990 1.05 1.01–1.09 5822 5724–5920
LA-LM 1.04 1.01–1.07 5799 5728–5871 0.01 1.04 1.01–1.07 5798 5726–5870 0.61
HA-HM 1.07 1.04–1.11 5870 5784–5957 0.32 1.06 1.02–1.10 5842 5738–5946 0.64
HA-LM (SO) 1.04 1.00–1.07 5790 5708–5872 0.004 1.02 0.98–1.05 5735 5650–5820 0.05
TrFM/ASM classificationc
<15th centile (reference) 1.10 1.05–1.15 5937 5819–6054 1.07 1.02–1.12 5858 5736–5979
15–84th centile 1.05 1.02–1.08 5829 5754–5903 0.01 1.04 1.01–1.07 5797 5721–5874 0.15
≥85th centile (SO) 1.05 1.02–1.08 5818 5750–5885 0.02 1.03 0.99–1.07 5767 5678–5857 0.16

Significant results are highlighted in bold.

aThe mean telomere length, relative to the reference DNA, was calculated and expressed as the mean T/S ratio.

bLA is low adiposity, HA is high adiposity, LM is low muscle mass and HM is high muscle mass.

cTrFM is truncal fat mass, ASM is appendicular skeletal mass.