Fig. 6.

Translation coupling attenuates action of KSG on translation initiation. (A) E. coli endogenous genes were divided into three categories: overlapping operonic genes (red) where the start codon of the downstream gene overlaps with the coding sequence or the stop codon of the upstream gene in the same operon; nonoverlapping operonic genes (blue); other genes (encoded in single-gene transcription units or the first genes in polycistronic operons). See SI Appendix, Supplementary Results and Discussion for details. (B) Violin plots comparing changes of TE in different gene categories in cells exposed to 10 mg/mL of KSG. Significance values from pair-wise t test comparison with Bonferroni adjustment are indicated as ****P < 0.0001; *P < 0.05.