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Motility of human T lymphoblastoid cells in response to monomeric and dimeric CXCL12. (A) Aggregated trajectories of the spontaneous motility of CCRF-HSB2 cells in the absence or presence of increasing concentrations of CXCL12 monomer or (CXCL12)2–Fc fusion protein were monitored by continuous live-cell imaging for 2 h. (B) The accumulated distance of each cell was calculated and plotted. Mean ± SEM; ns, not significant; **P < 0.01, ****P < 0.0001, Student’s t test.
