TABLE 1.
Species (no. of isolates) | MIC (μg/ml) of fluconazoleb
|
MIC (μg/ml) of voriconazoleb
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Range | Median | Geometric mean | 50% | 90% | Range | Median | Geometric mean | 50% | 90% | |
C. albicans (82) | 0.094–4 | 0.25 | 0.28 | 0.25 | 0.5 | 0.004–0.38 | 0.012 | 0.013 | 0.015 | 0.015 |
C. glabrata (19) | 2–32 | 12 | 14 | 16 | 32 | 0.125–2 | 0.5 | 0.52 | 0.5 | 2 |
C. krusei (3) | 64–128 | 64 | 80 | 64 | 128 | 0.75–1.5 | 0.75 | 1.26 | 1 | 2 |
C. lusitaniae (2) | 1.5–3 | 2.25 | 2.83 | 2 | 4 | 0.047–0.064 | 0.0555 | 0.06 | 0.06 | 0.06 |
C. parapsilosis (5) | 0.38–2 | 0.75 | 1 | 1 | 2 | 0.016–0.032 | 0.032 | 0.027 | 0.03 | 0.03 |
C. tropicalis (3) | 0.5–1 | 0.625 | 0.707 | 0.5 | 1 | 0.032–0.125 | 0.095 | 0.073 | 0.06 | 0.125 |
MICs of strains were determined using the E-test according to the instructions of the manufacturer.
Range and median calculated on full range of MICs from E-tests. 50% and 90%, MIC50 and MIC90, respectively.