Table 2.
Association of immune cell infiltrate with clinicopathological variables and immunohistochemistry (IHC)
| Immune cell infiltrate | |||||
|---|---|---|---|---|---|
| Low | Median | High | p | ||
| Tumor stage | pT1a | 0 | 10 | 13 | 0.0426 |
| pT1b | 0 | 1 | 6 | ||
| pT2 | 2 | 10 | 11 | ||
| pT3 | 1 | 2 | 0 | ||
| pT4 | 1 | 0 | 1 | ||
| Nodal status | pN0 | 0 | 8 | 5 | 0.0881 |
| pN > 0 | 2 | 2 | 5 | ||
| Grading | G1 | 1 | 4 | 7 | 0.8113 |
| G2 | 2 | 17 | 20 | ||
| G3 | 1 | 3 | 5 | ||
| Infiltration pattern | Infiltrative pattern | 2 | 17 | 19 | 0.5773 |
| Pushing margin | 2 | 7 | 13 | ||
| Morphological tumor type | Usual | 3 | 23 | 28 | 0.2098 |
| Basaloid | 1 | 1 | 4 | ||
| HPV status | Negative | 2 | 13 | 10 | 0.3736 |
| Low risk | 0 | 1 | 1 | ||
| High risk | 2 | 9 | 20 | ||
| PD-L1 IHC | TPS 0% | 1 | 0 | 3 | 0.1193 |
| (n = 30) | TPS > 0% ≤ 10% | 1 | 7 | 6 | |
| TPS > 10% | 0 | 3 | 9 | ||
| PD-L1 IHC | IC 0% | 2 | 0 | 0 | 0.0017 |
| (n = 30) | IC > 0% ≤ 10% | 0 | 5 | 14 | |
| IC > 10% | 0 | 5 | 4 | ||
| PD-L1 IHC | CPS 0 | 1 | 0 | 0 | 0.0382 |
| (n = 30) | CPS ≥ 0 ≤ 10 | 1 | 2 | 7 | |
| CPS > 10 | 0 | 8 | 11 | ||
| p16 IHC | Negative | 2 | 14 | 13 | 0.4307 |
| Positive | 2 | 10 | 19 | ||