Table 2.
Characteristics of patients with and without sarcopenia
Total | Sarcopenic | Non sarcopenic | χ2 | p value | ||||
---|---|---|---|---|---|---|---|---|
N = 73 | N = 24 | N = 49 | ||||||
Age (years) (M, SD) | 81.73 | 6.24(SD) | 83.7 | 5.73(SD) | 80.24 | 6.21(SD) | NA | 0.025 |
Sex (n, %) | ||||||||
Male | 33 | 45 | 10 | 42 | 23 | 47 | 0.181 | 0.671 |
Female | 40 | 55 | 14 | 58 | 26 | 53 | ||
Weight loss 6 months prior to diagnosis (n, %) | ||||||||
Non | 46 | 63 | 15 | 63 | 31 | 63 | 0.392 | 0.822 |
< 10% | 20 | 27 | 6 | 25 | 14 | 29 | ||
≥ 10% | 7 | 10 | 3 | 13 | 4 | 8 | ||
BMI (kg/m2) | 26.80 | 5.70(SD) | 25.12 | 4.99(SD) | 27.92 | 4.49(SD) | NA | 0.018 |
Smoker (n, %) | ||||||||
No | 25 | 34 | 11 | 46 | 14 | 29 | 2.604 | 0.272 |
Former | 40 | 55 | 10 | 42 | 30 | 61 | ||
Current | 8 | 11 | 3 | 13 | 5 | 10 | ||
MUST score (n, %) | ||||||||
0 | 53 | 72 | 18 | 75 | 35 | 71 | 0.533 | 0.766 |
1 | 1 | 2 | 0 | 0 | 1 | 2 | ||
2 | 19 | 26 | 6 | 25 | 13 | 27 | ||
Alcohol use (n, %) | ||||||||
No | 25 | 34 | 9 | 38 | 16 | 33 | 1.340 | 0.720 |
Yes | 41 | 56 | 14 | 58 | 27 | 55 | ||
Former | 7 | 10 | 1 | 4 | 6 | 12 | ||
Charlson comorbidity index (n, %) | ||||||||
Low ≤ 6 | 27 | 37 | 6 | 25 | 21 | 43 | 2.204 | 0.138 |
High > 6 | 46 | 63 | 18 | 75 | 28 | 57 | ||
Localization (n, %) | ||||||||
Oral cavity | 46 | 63 | 14 | 58 | 32 | 65 | 12.284 | 0.584 |
Nasopharynx | 2 | 3 | 1 | 4 | 1 | 2 | ||
Oropharynx | 2 | 3 | 0 | 0 | 2 | 4 | ||
Hypopharynx | 3 | 4 | 1 | 4 | 2 | 4 | ||
Larynx | 7 | 10 | 2 | 8 | 5 | 10 | ||
Skin | 8 | 11 | 3 | 13 | 5 | 10 | ||
Paranasal sinuses | 2 | 2 | 1 | 4 | 2 | 4 | ||
Type of tumor (n, %) | ||||||||
Primary | 56 | 77 | 17 | 71 | 39 | 80 | 1.019 | 0.601 |
Recurrent | 11 | 15 | 4 | 17 | 7 | 14 | ||
Second primary | 6 | 8 | 3 | 13 | 3 | 6 | ||
TNM Stage (n, %) | ||||||||
I | 8 | 11 | 5 | 21 | 3 | 6 | 3.708 | 0.295 |
II | 19 | 26 | 5 | 21 | 14 | 29 | ||
III | 14 | 19 | 4 | 17 | 10 | 20 | ||
IV | 32 | 44 | 10 | 42 | 22 | 45 | ||
Low Muscle strength (n, %) | ||||||||
No | 40 | 55 | 0 | 0 | 40 | 82 | 43.340 | 0.000 |
Yes | 33 | 45 | 24 | 100 | 9 | 18 | ||
Low SMI (n, %) | ||||||||
No | 15 | 21 | 0 | 0 | 15 | 31 | 9.247 | 0.002 |
Yes | 58 | 79 | 24 | 100 | 34 | 69 | ||
Frailty Fried criteria (n, %) | ||||||||
No | 52 | 71 | 10 | 42 | 42 | 86 | 15.253 | 0.000 |
Yes | 21 | 29 | 14 | 58 | 7 | 14 | ||
Frailty GFI (n, %) | ||||||||
No | 35 | 50 | 9 | 38 | 26 | 53 | 1.563 | 0.211 |
Yes | 38 | 52 | 15 | 63 | 23 | 47 | ||
Frailty CGA (n, %) | ||||||||
No | 34 | 46 | 7 | 29 | 27 | 55 | 4.355 | 0.037 |
Yes | 39 | 54 | 17 | 71 | 22 | 45 |
BM body mass index, MUST malnutrition universal screening tool, SMI skeletal muscle index, GFI groningen frailty indicator, CGA comprehensive geriatric assessment