. 2021 Mar 10;279(2):723–737. doi: 10.1007/s00405-021-06719-3

Table 3.

Studies with wait-and-see policy (n = 3, 207 patients)

Author	Age	Sex	Location TMR	Follow-up	Remission TMR (%)	Audiometry (dB, ABG)	Other remarks
Bayoumy [4] (n = 81)	23 (14–47)	M: 42 F: 39	PT/PF	64 months	96% with improved or stable TMRs 10% complete remission	First-visit: 17.9 dB Last visit: 15.5 dB Audiometry by Sade grade was provided in the study	Progression to CST in 1 (1%) Progression to perforation in 5 (6%)
Parkes [3] (n = 37)	15 (9–21)	N.R.	PT	6.4 years (0.75–7.6)	76% with improved or stable TMRs	Initial PTA stable/improved: 11.2 dB	Progression to CST in 2 (5%)
Cutajar [29] (n = 89)	12.6	N.R.	PT	10 years	No adult ear in remission 20 children ears improved (31%)	N.R.	The proportion of children whose ears improved at 5 years was 0.19 (CI 0.09–0.29), which increased to 0.56 (CI 0.38–0.74) by 10 years

Author

Age

Sex

Location TMR

Follow-up

Remission TMR (%)

Audiometry (dB, ABG)

Other remarks

Bayoumy [4] (n = 81)

23 (14–47)

M: 42

F: 39

PT/PF

64 months

96% with improved or stable TMRs

10% complete remission

First-visit: 17.9 dB

Last visit: 15.5 dB

Audiometry by Sade grade was provided in the study

Progression to CST in 1 (1%)

Progression to perforation in 5 (6%)

Parkes [3] (n = 37)

15 (9–21)

N.R.

6.4 years (0.75–7.6)

76% with improved or stable TMRs

Initial PTA stable/improved: 11.2 dB

Progression to CST in 2 (5%)

Cutajar [29] (n = 89)

12.6

N.R.

10 years

No adult ear in remission

20 children ears improved (31%)

N.R.

The proportion of children whose ears improved at 5 years was 0.19 (CI 0.09–0.29), which increased to 0.56 (CI 0.38–0.74) by 10 years

PT pars tensa, PF pars flaccida, CST cholesteatoma