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. 2022 Jan 27;79(2):96. doi: 10.1007/s00018-021-04108-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Model illustrating the possible role of MyoVc and Spire1 in WPB exocytosis. During maturation, MyoVc and Spire1 are recruited to WPB via Rab3 and/or Rab27a. Upon secretagogue stimulation WPB undergo exocytosis, with or without the appearance of actin rings. The latter involves the action of Spire1 and MyoVc which are also present in the ring-like structures. Created with BioRender.com