Table 4.
Changes in fatty acid composition in serum after weight loss (WL) achieved by laparoscopic sleeve gastrectomy (LSG)
| Fatty acids (%) | Baseline | After WL | Change | p value |
|---|---|---|---|---|
| SFA | ||||
| C6:0 (caproic) | n.d | n.d | - | - |
| C8:0 (caprylic) | 1.47 ± 0.57 | 1.13 ± 0.80 | -0.34 | 0.04 |
| C10:0 (capric) | 1.67 ± 0.48 | 1.21 ± 0.69 | -0.46 | 0.01 |
| C11:0 (undecylic) | n.d | n.d | - | - |
| C12:0 (lauric) | 0.92 ± 0.26 | 0.64 ± 0.33 | -0.28 | 0.00 |
| C13:0 (tridecylic) | 0.13 ± 0.19 | 0.12 ± 0.13 | -0.01 | 0.82 |
| C14:0 (myristic) | 0.80 ± 0.34 | 0.63 ± 0.32 | -0.18 | 0.03 |
| C15:0 (pentadecanoic) | 0.18 ± 0.05 | 0.19 ± 0.06 | 0.00 | 0.69 |
| C16:0 (palmitic) | 25.81 ± 2.74 | 23.68 ± 2.41 | -2.13 | 0.00 |
| C17:0 (margaric) | 0.25 ± 0.09 | 0.25 ± 0.07 | 0.00 | 0.81 |
| C18:0 (stearic) | 6.62 ± 0.84 | 6.51 ± 0.61 | -0.11 | 0.47 |
| C20:0 (arachidic) | 0.05 ± 0.04 | 0.06 ± 0.09 | 0.02 | 0.47 |
| C21:0 (heneicosylic) | 0.17 ± 0.07 | 0.15 ± 0.04 | -0.02 | 0.27 |
| C22:0 (behenic) | n.d | n.d | - | - |
| C23:0 (tricosylic) | 0.24 ± 0.10 | 0.14 ± 0.09 | -0.10 | 0.00 |
| C24:0 (lignoceric) | 0.05 ± 0.01 | 0.04 ± 0.01 | -0.01 | 0.30 |
| MUFA | ||||
| C14:1 n-5 (myristoleic) | 0.04 ± 0.02 | 0.03 ± 0.02 | -0.02 | 0.00 |
| C15:1 n-10 (pentadecenoic) | n.d | n.d | - | - |
| C16:1 n-7 (palmitoleic) | 3.16 ± 0.74 | 2.24 ± 0.80 | -0.91 | 0.00 |
| C17:1 n-10 (margarolein) | 0.24 ± 0.10 | 0.26 ± 0.15 | 0.02 | 0.58 |
| C18:1 trans n-9 (elaidic) | 0.20 ± 0.15 | 0.10 ± 0.04 | -0.10 | 0.03 |
| C18:1 cis n-9 (oleic) | 24.52 ± 1.97 | 24.14 ± 2.60 | -0.38 | 0.39 |
| cis-11 C20:1 n-9 (eicosenoic) | 0.18 ± 0.05 | 0.22 ± 0.09 | 0.04 | 0.01 |
| cis-13 C22:1 n-9 (erucic) | 0.02 ± 0.00 | n.d | - | - |
| C24:1 n-9 (nervonic) | n.d | n.d | - | - |
| PUFA | ||||
| C18:2 n-9 (linolelaidic) | 3.07 ± 0.32 | 2.93 ± 0.37 | -0.14 | 0.11 |
| C18:2 n-6 (LA; linoleic) | 20.63 ± 3.32 | 24.37 ± 4.26 | 3.74 | 0.00 |
| C18:3 n-6 (GLA; γ-linolenic) | 0.17 ± 0.13 | 0.16 ± 0.09 | -0.01 | 0.61 |
| C18:3 n-3 (ALA; α-linolenic) | 0.53 ± 0.19 | 0.51 ± 0.33 | -0.02 | 0.78 |
| c9,t11-CLA (conjugated linoleic) | 0.09 ± 0.03 | 0.10 ± 0.06 | 0.01 | 0.54 |
| C20:2 n-6 (eicosadienoic) | 0.09 ± 0.05 | 0.10 ± 0.06 | 0.01 | 0.41 |
| C20:3 n-6 (dihomo-γ-linolenic) | 0.96 ± 0.24 | 0.95 ± 0.24 | -0.01 | 0.79 |
| C20:3 n-3 (eicosatrienoic) | 0.25 ± 0.35 | 0.16 ± 0.14 | -0.08 | 0.62 |
| C20:4 n-6 (AA; arachidonic) | 3.47 ± 1.14 | 4.68 ± 1.41 | 1.21 | 0.00 |
| C20:5 n-3 (EPA; eicosapentaenoic) | 0.34 ± 0.20 | 0.34 ± 0.15 | 0.01 | 0.82 |
| C22:2 n-6 (docosadienoic acid) | 0.34 ± 0.18 | 0.22 ± 0.17 | -0.12 | 0.11 |
| C22:6 n-3 (DHA; docosahexaenoic) | 0.71 ± 0.34 | 0.90 ± 0.41 | 0.19 | 0.00 |
| Total content | ||||
| ∑ SFA | 38.20 ± 3.11 | 34.61 ± 2.93 | - 3.60 | 0.00 |
| ∑ MUFA | 28.35 ± 2.35 | 26.97 ± 3.09 | - 1.39 | 0.01 |
| ∑ PUFA | 30.45 ± 4.23 | 35.27 ± 5.57 | 4.82 | 0.00 |
| ∑ n-3 | 1.69 ± 0.68 | 1.80 ± 0.77 | -0.11 | 0.39 |
| ∑ n-6 | 25.19 ± 4.20 | 30.18 ± 5.45 | 4.99 | 0.00 |
| n-6/n-3 | 16.91 ± 6.01 | 18.87 ± 6.27 | -1.95 | 0.09 |
Data expressed as mean ± SD; p values were considered significant when p < 0.05 (in bold). Values at baseline were compared with post‐surgery values using paired t-test